Table of Content Details

Abstract

Objective: Preeclampsia is a leading cause of maternal and perinatal morbidity and mortality,
characterized by new-onset hypertension after 20 weeks of gestation. This study explores
the maternal and perinatal outcomes associated with organ involvement in preeclampsia,
focusing on identifying complications and their effects.
Materials and Methods: This prospective observational analytical study was conducted
over 18 months at a tertiary care hospital in Kolkata. A total of 106 pregnant women
diagnosed with preeclampsia beyond 20 weeks of gestation were included. Exclusion criteria
encompassed pre-existing renal or liver disease, multifetal gestation, and other conditions
potentially confounding the study.
Results: Renal dysfunction was observed in 6.6% of cases, characterized by proteinuria and,
in severe cases, acute kidney injury. Hepatic dysfunction, including elevated liver enzymes
and HELLP syndrome, occurred in 10.4% of participants, similarly lung involvement
characterized by basal lung crepitations suggestive of pulmonary edema, indicative of
severe fluid overload, was seen in 10.4%. Multi-organ dysfunction was documented in
1.88% of cases, significantly correlating with adverse maternal outcomes such as increased
cesarean deliveries (34.9%), maternal ICU admissions, and higher perinatal complications.
NICU admissions were required in 54.7% of neonates, with 41.5% exhibiting fetal growth
restriction and 7.5% neonatal mortality.

Click Here For Reading Continue

Download Journal